RFWD3 Polyclonal Antibody, 20ul Electronic Pipette The gene encoding leucine zipper

The gene encoding leucine zipper protein down-regulated in cancer cells-like 1 (LDOC1L) is present on chromosome Xq27

and in a dimeric or multimeric form at the cell surface and in extracellular matrix

250mL*4pcs

Contributes to cell motility by controlling actin dynamics

The microsatellite is polymorphic

RFWD3 Polyclonal Antibody, 20ul Electronic Pipette The gene encoding leucine zipperRFWD3, also named as RNF201, is a E3 ubiquitin protein ligase that mediates the ubiquitination of p53 TP53 in the late response to DNA damage, and acts as a positive regulator of p53 TP53 stability, thereby regulating the G1 S DNA damage checkpoint. RFWD3 may act by catalyzing the formation of short polyubiquitin chains on p53 TP53 that are not targeted to the proteasome. In response to ionizing radiation, It interacts with MDM2 and enhances p53 TP53