CLD23 Polyclonal Antibody, 50ul Digital Burette Members of this family are

Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation

This gene is aberrantly methylated in pancreatic cancer

Enhances the transcriptional repressor activity of NR1D1 through stabilization of NR1D1 protein levels by preventing its ubiquitination and subsequent degradation (PubMed: 18235501

Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration

in addition to a DNA-binding homeodomain

CLD23 Polyclonal Antibody, 50ul Digital Burette Members of this family areThis gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B cells, placenta