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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Phosphorylation at Ser-425 and Ser-428

SKU: 49318005994

4.2
USD162.00 USD187.00

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Phosphorylation at Ser-425 and Ser-428BRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary

Diseases associated with GLB1L3 include leber congenital amaurosis

Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes

This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15

and is thought to be required for DNA replication from viral origin of replication

BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Phosphorylation at Ser-425 and Ser-428BRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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