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Be realistic about lifestyle intensification requirements

Any changes observed are likely secondary to the metabolic and weight-related effects of the medication rather than a direct pharmacological action on the reproductive system

J Clin Endocrinol Metab (2020) 105:e27106

Logistic regression was used to evaluate whether male and female participants differed in achieving specific weight loss milestones, including reductions of 5%, 10%, and 15% of their body weight