HRK Polyclonal Antibody, 50ul Vacuum Filter MARCH3 encodes a member of

MARCH3 encodes a member of the membrane-associated RING-CH (MARCH) family

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and a leucine-rich repeat (LRR) motif

in humans| loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors

although its role in tumor formation has not been determined

HRK Polyclonal Antibody, 50ul Vacuum Filter MARCH3 encodes a member ofThis gene encodes a member of the BCL 2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL 2 and BCL X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants.