EGFL4 Polyclonal Antibody, 20ul Vacuum Aspirator ABCA6 is clustered among 4

ABCA6 is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis

The encoded protein also plays a prominent role in the activation of the Notch signaling pathway

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mutations in CHEK2 are thought to confer a predisposition to sarcomas

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EGFL4 Polyclonal Antibody, 20ul Vacuum Aspirator ABCA6 is clustered among 4Multiple EGF like domains 8 encoded by MEGF8 is a single pass type I membrane protein of unknown function that contains several EGF like domains, Kelch repeats, and PSI domains. Defects in MEGF8 are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for MEGF8.