ARAP1 Polyclonal Antibody, 100ul Immunology Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been described for PARD3

Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system

and more selectively in adult tissues

The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts

Each laminin chain is a multidomain protein encoded by a distinct gene

ARAP1 Polyclonal Antibody, 100ul Immunology Multiple alternatively spliced transcript variantsThe protein encoded by this gene contains SAM, ARF GAP, RHO GAP, ankyrin repeat, RAS associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) dependent ARF GAP activity. The encoded protein associates with the Golgi, and the ARF GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell specific trafficking of a