BMPER Polyclonal Antibody, 20ul Molecular Sciences LIFR encodes leukemia inhibitory factor

LIFR encodes leukemia inhibitory factor receptor alpha that belongs to the type I cytokine receptor family

Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease

Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder

Mutations in NOTCH4 may be associated with schizophrenia

which activates p53 and initiates apoptosis

BMPER Polyclonal Antibody, 20ul Molecular Sciences LIFR encodes leukemia inhibitory factorThis gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2 and BMP4 dependent osteoblast differentiation and BMP dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.