CBX2 Polyclonal Antibody, 50ul CellSafe™ The high mobility group nucleosomal

The high mobility group nucleosomal binding domain 2 encoded by HMGN2 binds nucleosomal DNA and is associated with transcriptionally active chromatin

The product of this gene is an enzyme involved in lipid metabolism| and it encodes cytosolic acetoacetyl-CoA thiolase

and has smooth inner and outer surfaces and a uniform gloss

Contains 2 protein kinase domains

The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein

CBX2 Polyclonal Antibody, 50ul CellSafe™ The high mobility group nucleosomalCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms