RN123 Polyclonal Antibody, 50ul Antibody Development CDK8 and CDC2L6/CDK11

CDK8 and CDC2L6/CDK11

called PPARs

Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation

and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27

It also plays a role in the WNT and PI3K signaling pathways

RN123 Polyclonal Antibody, 50ul Antibody Development CDK8 and CDC2L6/CDK11The protein encoded by this gene contains a C terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein protein and protein DNA interactions, and an N terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants.