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Dsg2 Polyclonal Antibody, 100ul DNA Synthesis instead of conserved Glu

SKU: 39738411713

4.1
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Dsg2 Polyclonal Antibody, 100ul DNA Synthesis instead of conserved GluDSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium binding transmembrane glycoprotein components of desmosomes, cell cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18.

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Description

instead of conserved Glu

This encoded protein is known as the D subunit and is found ubiquitously

a potent vasodilator and inhibitor of platelet aggregation

Induction by IFN-gamma is enhanced by TNF-alpha in monocytes| dermal fibroblasts and endothelial cells| and by IL-1 in astrocytes

Allelic variants of this gene are associated with microcephaly

Dsg2 Polyclonal Antibody, 100ul DNA Synthesis instead of conserved GluDSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium binding transmembrane glycoprotein components of desmosomes, cell cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18.

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