ALKB3 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Overexpression of this gene in

Overexpression of this gene in COS7 cells stimulates translation

Contains 3 Ig-like C2-type (immunoglobulin-like) domains

|Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family

a disorder characterized by mental retardation

This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis

ALKB3 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Overexpression of this gene inThe Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1 methyladenine and 3 methylcytosine (Duncan et al., 2002