FAK(Phospho Tyr861) Polyclonal Antibody, 50ul Custom DNA Oligos The protein encoded by this

The protein encoded by this gene belongs to the SAC domain-containing protein gene family

with the last serine residue replaced by alanine

NF-κB-activating agents can induce the phosphorylation of IκB proteins

Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome

suggesting a cell cycle function

FAK(Phospho Tyr861) Polyclonal Antibody, 50ul Custom DNA Oligos The protein encoded by thisThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal