BAGE5 Polyclonal Antibody, 100ul Antibodies The J domain mediates the

The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity

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and differentiation and it may also play a role in the cell cycle progession

Mutations in this gene have been associated with microencephaly| cortical malformations| and mental retardation

BAGE5 Polyclonal Antibody, 100ul Antibodies The J domain mediates theBAG family molecular chaperone regulator 5 encoded by BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C terminus, which could bind and