Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy Another member of the CHP

Another member of the CHP subfamily

and possesses ubiquitin ligase E3 activity

This gene encodes a member of the forkhead class of DNA-binding proteins

It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro

May be involved in necrotic or autophagic cell death

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy Another member of the CHPThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.