Hamartin Polyclonal Antibody, 50ul Cell Culture Flasks suggesting co-operative transcriptional regulation of

suggesting co-operative transcriptional regulation of these two functionally related genes

VAV1 (vav guanine nucleotide exchange factor 1) is a member of the VAV gene family

Alternatively splicing results in multiple transcript variants| including the DM20 splice variant

The protein encoded by this gene is a member of the APBB protein family

is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation

Hamartin Polyclonal Antibody, 50ul Cell Culture Flasks suggesting co-operative transcriptional regulation ofTSC1 (tuberous sclerosis 1) encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.