SMG7 Polyclonal Antibody, 50ul Dry Bath The encoded protein may function

The encoded protein may function as a transcription factor

The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel

induction:Upon B-cell activation

and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis

A pseudogene of IRX1 is located on chromosome 13

SMG7 Polyclonal Antibody, 50ul Dry Bath The encoded protein may functionSMG7 encodes protein SMG7 that is essential for nonsense mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C terminal domain interacts with the mRNA decay