CMBL Rabbit Polyclonal Antibody, 50ul Peptide Synthesis Dynein axonemal light chain 1

Dynein axonemal light chain 1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella

The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family

This protein binds and hydrolyzes ATP| may function as a 5'-polynucleotide kinase| and has the capacity to be a ubiquitylation substrate

each encoding a distinct isoform

miscellaneous:The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide

CMBL Rabbit Polyclonal Antibody, 50ul Peptide Synthesis Dynein axonemal light chain 1CMBL (EC 3. 1. 1. 45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters and it activates medoxomil ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al. 2010