HGFL Polyclonal Antibody, 100ul Apoptosis & Autophagy Involved in the PP6-mediated dephosphorylation

Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha

MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease

PSCA is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas

Although alternative splicing has been observed

An important paralog of this gene is CYB5R3

HGFL Polyclonal Antibody, 100ul Apoptosis & Autophagy Involved in the PP6-mediated dephosphorylationThe protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and