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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging and a C-terminal cytoplasmic domain

SKU: 3478439338

4.2
USD141.00 USD161.00

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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging and a C-terminal cytoplasmic domainTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

and a C-terminal cytoplasmic domain

thereby releasing the attached protein from the plasma membrane

and is considered to be an oncogene

guanine nucleotide exchange factors (GEFs)

Widely expressed in fetal tissues

p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging and a C-terminal cytoplasmic domainTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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