LAP2A Polyclonal Antibody, 20ul Lentiviral Packaging The proline-rich domain may interact

The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding

and thus may function as a regulator of Rho signaling pathways

which then activates a specific MAPK

Unlike other proteins in this family

and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients

LAP2A Polyclonal Antibody, 20ul Lentiviral Packaging The proline-rich domain may interactThymopoietin encoded by TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.