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PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 100ul Nucleic Acid Amplification Two alternately spliced transcript variants

SKU: 32233335134

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PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 100ul Nucleic Acid Amplification Two alternately spliced transcript variantsThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

Two alternately spliced transcript variants of MAPKAPK5 encoding distinct isoforms have been reported

The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter

Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase

The protein encoded by SSTR1 (somatostatin receptor 1) is a member of the superfamily of somatostatin receptors having seven transmembrane segments

' includes an extracellular domain with several putative protein-protein interaction domains

PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 100ul Nucleic Acid Amplification Two alternately spliced transcript variantsThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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