RGS17 Polyclonal Antibody, 100ul Bottles Mutations in this gene cause

Mutations in this gene cause cortical dysplasia

The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes

which required for microtubule nucleation at the centrosome

this protein contains an SH2 domain flanked by two SH3 domains

a protein phosphatase-1-interacting domain

RGS17 Polyclonal Antibody, 100ul Bottles Mutations in this gene causeThis gene encodes a member of the regulator of G protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine rich region. The protein attenuates the signaling activity of G proteins by binding to activated, GTP bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta