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DPM3 Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables ETV6 is known to be

SKU: 28014560422

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DPM3 Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables ETV6 is known to beDolichol phosphate mannose (Dol P Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol P Man results in defective surface expression of GPI anchored proteins. Dol P Man is synthesized from GDP mannose and dolichol phosphate on the cytosolic side of the ER by the enzyme dolichyl phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl phosphate mannosyltransferase

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Description

ETV6 is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma

and its gene mutation and increased expression may be associated with human cancer

This gene is located at the 5' end of the HOXD gene cluster on chromosome 2

5ml x 60 Centrifuge Tube Disk

suggesting a role in tumor development and metastasis

DPM3 Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables ETV6 is known to beDolichol phosphate mannose (Dol P Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol P Man results in defective surface expression of GPI anchored proteins. Dol P Man is synthesized from GDP mannose and dolichol phosphate on the cytosolic side of the ER by the enzyme dolichyl phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl phosphate mannosyltransferase

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