Rat Growth/Differentiation Factor 11, GDF11 ELISA Kit, 96T DNA/RNA Isolation & Purification a member of the class

a member of the class II cytokine receptor family

BPTI/Kunitz inhibitor and E2 domains in the middle region

This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm

Also involved in the integration of the circadian rhythms and energy metabolism

Plays a role in the circadian regulation of body temperature and negatively regulates thermogenic transcriptional programs in brown adipose tissue (BAT)

Rat Growth/Differentiation Factor 11, GDF11 ELISA Kit, 96T DNA/RNA Isolation & Purification a member of the classSecreted signal that acts globally to specify positional identity along the anterior posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Signals through activin receptors type 2, ACVR2A and ACVR2B, and activin receptors type 1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.