TP53INP2 Polyclonal Antibody, 100ul[BT-AP09143] Variant Libraries Aberrant expression of this gene

Aberrant expression of this gene is associated with cancer progression in multiple tissues

Intracellularly

Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction

|subunit:Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein Bcl-2

The encoded protein interacts with TP53

TP53INP2 Polyclonal Antibody, 100ul[BT-AP09143] Variant Libraries Aberrant expression of this geneThe protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1 RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes.