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ECEL1 Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser PARP4 encodes poly(ADP-ribosyl)transferase-like 1 protein

SKU: 24314369166

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ECEL1 Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser PARP4 encodes poly(ADP-ribosyl)transferase-like 1 proteinThis gene encodes a member of the M13 family of endopeptidases. Members of this family are zinc containing type II integral membrane proteins that are important regulators of neuropeptide and peptide hormone activity. Mutations in this gene are associated with autosomal recessive distal arthrogryposis type 5D. This gene has multiple pseudogenes on chromosome 2. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

PARP4 encodes poly(ADP-ribosyl)transferase-like 1 protein

The encoded protein plays an important role in maintaining stem cell populations| and may be aberrantly expressed in tumor cells

May regulate B-cell antigen receptor-mediated signaling

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

ABHD2 encodes a protein (abhydrolase domain containing 2) containing an alpha/beta hydrolase fold

ECEL1 Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser PARP4 encodes poly(ADP-ribosyl)transferase-like 1 proteinThis gene encodes a member of the M13 family of endopeptidases. Members of this family are zinc containing type II integral membrane proteins that are important regulators of neuropeptide and peptide hormone activity. Mutations in this gene are associated with autosomal recessive distal arthrogryposis type 5D. This gene has multiple pseudogenes on chromosome 2. Alternative splicing results in multiple transcript variants encoding different isoforms.

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