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PLB Polyclonal Antibody, 100ul Immunology Growth associated protein 43 encoded

SKU: 24059296016

4.3
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PLB Polyclonal Antibody, 100ul Immunology Growth associated protein 43 encodedThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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Description

Growth associated protein 43 encoded by GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration

and it therefore likely functions in spermatid formation

disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2)

when complexed to CAK

The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini

PLB Polyclonal Antibody, 100ul Immunology Growth associated protein 43 encodedThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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