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Ku-70 Polyclonal Antibody, 100ul[BT-AP04892] Cell Dissociation The protein acts as a

SKU: 2375874673

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Ku-70 Polyclonal Antibody, 100ul[BT-AP04892] Cell Dissociation The protein acts as aThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family

Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG

Mutations in GJA1 have been associated with oculodentodigital dysplasia

|PTM:Phosphorylated

and neural tube

Ku-70 Polyclonal Antibody, 100ul[BT-AP04892] Cell Dissociation The protein acts as aThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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