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DBC-1 Polyclonal Antibody, 100ul Liquid Storage Consumables Glial cell line-derived neurotrophic factor

SKU: 21838213645

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DBC-1 Polyclonal Antibody, 100ul Liquid Storage Consumables Glial cell line-derived neurotrophic factorCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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Description

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related

Alternatively-spliced transcript variants have been observed

Subunit A associates with a tight dimer composed of the B and C subunits

Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam

The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB)| both anchored in the membrane

DBC-1 Polyclonal Antibody, 100ul Liquid Storage Consumables Glial cell line-derived neurotrophic factorCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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