HMG-17 (Acetyl Lys31) Rabbit Polyclonal Antibody, 50ul Proteases The A-kinase anchoring protein 11

The A-kinase anchoring protein 11 is expressed at high levels throughout spermatogenesis and in mature sperm

Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth

This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption

Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7)

JunB is a basic region

HMG-17 (Acetyl Lys31) Rabbit Polyclonal Antibody, 50ul Proteases The A-kinase anchoring protein 11The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein HMGN1 the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria viruses and fungi.