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Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism

This is one of the main differences between AOD-9604 and full-length human growth hormone

While GLP-1 and GIP receptor agonists are highly effective for initiating caloric deficits, human metabolism is highly adaptive

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Unlike GHK-Cu, which occurs naturally in the human body and has broad skin research behind it, AHK-Cu was designed with hair biology in mind - particularly its potential to interact with the Wnt/-catenin signalling pathway involved in hair follicle cycling