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p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder Mutations in this gene are

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p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder Mutations in this gene areTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1)

PTM:Palmitoylation is critical for proper membrane localization and signaling

SspDl requires a longer incubation time for complete digestion of the DNA substrate

and a short C-terminal cytoplasmic domain that interacts with adaptor molecules

The gamma-glutamyltransferase 7 encoded by GGT7 consists of a heavy and a light chain

p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder Mutations in this gene areTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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