Fer(Phospho Tyr402) Polyclonal Antibody, 50ul Cellular Function Assays The first mRNA transcript isolated

The first mRNA transcript isolated for GCFC2 (GC-rich sequence DNA-binding factor 2) was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204)

The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures

and that loss of this protection results in cell death and sensorineural hearing loss

Inactivating variants of this gene result in the recessive Lutheran null phenotype

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Fer(Phospho Tyr402) Polyclonal Antibody, 50ul Cellular Function Assays The first mRNA transcript isolatedThe protein encoded by this gene is a member of the FPS FES family of non transmembrane receptor tyrosine kinases. It regulates cell cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X.