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Epidermal H(2)O(2) accumulation alters tetrahydrobiopterin (6BH4) recycling in vitiligo: identification of a general mechanism in regulation of all 6BH4-dependent processes

Zhang X, Yin M, Zhang LJ

At the molecular level, TMP269 inhibits the increased expressions of HDAC4 and acetyl-histone H3 induced by FA and I/R and reduces the expression of caspase-3 cleavage, Bax, and phosphorylation of p53