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Neurofibromatosis type 2 Like NF1 , autosomal dominant and sporadic mutations of the NF2 gene are equally common

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128 Additionally, thalidomide inhibits M1 macrophage polarization by targeting the transcription factor IRF5, reduces the release of inflammatory signals, significantly reduces the secretion of the proinflammatory cytokines IL-12 and IFN-, and promotes intestinal mucosal healing