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Mounjaro (Tirzepatide Injection) WARNING: RISK OF THYROID C-CELL TUMORS BLACK BOX WARNING: GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome type Do not take them if you have ever had thyroid cancer

Postmarketing Experience The following adverse reactions have been reported: Neurologic Reactions: Seizures have been reported to occur in patients, with or without pre-existing seizure activity, receiving either oral or intravenous levocarnitine

Important reminder : Each Mounjaro or Zepbound pen is a single-dose device that should be discarded immediately after injection

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Adv Exp Med Biol 1030:VIx Sylvestre M, Lv SX, Yang LF, Luera N, Peeler DJ, Chen BM, Roffler SR, Pun SH (2021) Replacement of L-amino acid peptides with D-amino acid peptides mitigates anti-PEG antibody generation against polymer-peptide conjugates in mice