CD48 Polyclonal Antibody, 100ul General Lab Use Probable E3 ubiquitin-protein ligase which

Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

an important regulator of blood pressure and electrolyte balance

The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor

SCF complexes| formed by SKP1 (MIM 601434)| cullin (see CUL1

|tissue specificity:Most abundant in heart| brain| liver| skeletal muscle and testis but absent in thymus and peripheral blood leukocytes

CD48 Polyclonal Antibody, 100ul General Lab Use Probable E3 ubiquitin-protein ligase whichCD48 encodes a member of the CD2 subfamily of immunoglobulin like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The CD48 antigen is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI