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Scenario 3: past expiration with questionable storage This is the worst combination

Abbreviations AHA/NHLBI: American Heart Association and the National Heart, Lung, and Blood Institute BMI: Body mass index CAD: Coronary artery disease DBP: Diastolic blood pressure F: Female FSG: Fasting serum glucose HbA1c: Glycated hemoglobin HDL: High-density lipoprotein iDeg: Insulin degludec iGlar: Insulin glargine GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide-1 M: Male MACE: Major adverse cardiovascular events MET: Metformin n: Number of patients in the specified category PBO: Placebo SBP: Systolic blood pressure SEMA: Semaglutide SGLT2i: Sodium-glucose co-transporter 2 inhibitor SU: Sulfonylurea T2D: Type 2 diabetes US: United States VLDL: Very-low-density lipoprotein WC: Waist circumference References Reaven GM

Tirzepatide has shown cardiovascular safety in people with type 2 diabetes, but personal risks should be evaluated by a healthcare provider

Muscle tissue is metabolically active, meaning it burns calories at rest and supports insulin sensitivity

These scheduled reviews prevent both impulsive dose changes and the opposite problem of staying at a suboptimal dose out of inertia