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Vitamin B6, a water-soluble vitamin (Rosenberg et al., 2017), may play a vital role in IBS and participate in inflammatory conditions (Ligaarden and Farup, 2011)

Histamine binding to H 2 receptors can activate PKA and induce tyrosinase pathway, and therefore melanogenesis process (Malaviya et al., 1996

Hereby, adequate chelation was defined for DFO subcutaneously (40 mg/kg/day in slow infusion over 812 h for at least 3 days per week), DFX (2030 mg/kg/day p.o.) or DFP (3075 mg/kg/day p.o.)

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