Neu Polyclonal Antibody, 100ul[BT-AP05904] Cell Dissociation The isoform type 3 does

The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms

FABPs may play roles in fatty acid uptake

|tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level)

Three distinct forms

Also found in epidermal basal layer keratinocytes in skin disorders

Neu Polyclonal Antibody, 100ul[BT-AP05904] Cell Dissociation The isoform type 3 doesERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those