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The predicted interaction footprint extends further toward the intracellular region, yielding a broad contact network that plausibly stabilizes an activation-compatible receptor architecture from the extracellular face toward the cytoplasmic side (Figure 4)

Originally designed to help people manage type 2 diabetes , these medications are now also being used to support healthy weight loss and improve overall wellness

As patients lose weight on GLP-1 therapy, increased mobility often becomes feasible, creating opportunities for enhanced physical activity that further supports weight management and joint function

This work was supported by Key research and development program in Xinjiang Uygur Autonomous Region (2022B03002-2), Tianshan Talent Training Program (2023TSYCLJ0043) and Key R&D Program Project in Xinjiang, Research on Key Technologies for Quality Control at the Source of Ancient Classic Prescriptions (2022B03007-2)