ALDH3A2 Monoclonal Antibody, 100ul Protein Research Studies suggest that the N-terminal

Studies suggest that the N-terminal region of this protein interacts with Atxn1 (GeneID:6310)

Additional alternatively spliced transcripts may exist

This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression

The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation

It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2

ALDH3A2 Monoclonal Antibody, 100ul Protein Research Studies suggest that the N-terminalAldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.