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This is the core idea behind Synchronicity Healths approach

Investment Strategy: Biologics LOE For institutional investors, the analytical question at a biologic LOE is not how much will biosimilars capture but rather: (1) what is the net price convergence trajectory between the reference product and biosimilar competitors under real-world formulary conditions, (2) does the innovator have pre-negotiated rebate contracts that lock in formulary position for 12 to 24 months post-launch, (3) what is the IP stack on the successor asset, and (4) how far along is the clinical conversion to a reformulated or combination version that carries fresh exclusivity

Bull ., 2017, vol

A randomised, double blind, placebo-controlled trial of a fixed dose of N -acetyl cysteine in children with autistic disorder

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