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Some studies demonstrated that the administration of antidepressants leads to an improvement in depressive mood through the increase of hippocampal neurogenesis and the enhancement of synaptic connectivity (Duman et al., 2001

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98 Similarly, exendin-4 also decreased the mRNA levels of IL-1 and TNF- in LPS-stimulated microglia, and significantly attenuated the activation of the NF-B signaling pathway

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