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Vandael D, Gounko NV (2019) Corticotropin releasing factor-binding protein (CRF-BP) as a potential new therapeutic target in Alzheimers disease and stress disorders

The mechanism also appears to preserve lean muscle mass, as the peptide does not promote protein catabolism or interfere with muscle protein synthesis pathways

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this difference in receptor binding may lead to a differential recruitment of downstream neuronal pathway in rodent models and in vivo body weight lowering effect