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AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis Consistent with this observation

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AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis Consistent with this observationAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with

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Description

Consistent with this observation

functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass

This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions

Alternatively spliced transcript variants encoding different isoforms have been found in GABRA4

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AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis Consistent with this observationAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with

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