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Name: tirzepatide with high blood pressure Effects of tirzepatide, a dual GIP and GLP-1 receptor agonist, on pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats Potential mechanisms by which tirzepatide
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doi: 10.1111/j.1365-3040.2008.01928.x

Currently licensed weight management treatments in the UK include orlistat (available on prescription and over the counter), and the GLP-1 receptor agonist semaglutide (Wegovy), which received MHRA approval for chronic weight management in adults and is supported by NICE technology appraisal TA875

10.3389/fphar.2016.00433 [DOI] [PMC free article] [PubMed] [Google Scholar] Drucker D

The dual incretin mechanism provides synergistic effects on appetite suppression, insulin secretion, and metabolic improvement

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