NU9056 - KAT5 (Tip60) Histone Acetyltransferase Inhibitor. CAS# 1450644-28-6 0147 having MTDs in mice and

having MTDs in mice and rats of >150 mg/ kg and 90 mg/kg in rats

It inhibits PHD2 via binding to the 2OG binding site

89464-63-1

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

916170-19-9

NU9056 - KAT5 (Tip60) Histone Acetyltransferase Inhibitor. CAS# 1450644-28-6 0147 having MTDs in mice andNU9056, CAS No. 1450644 28 6, is a selective KAT5 (Tip60) histone acetyltransferase inhibitor that inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. NU9056 also decreases proliferation of LNCaP cells and induces apoptosis via caspase activation. Product information CAS Number: 1450644 28 6 Molecular Weight: 232. 37 Formula: C6H4N2S4 Chemical Name: 1,2 di(isothiazol 5 yl)disulfane Smiles: C1C=NSC=1SSC1=CC=NS1