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Chronic glutamate toxicity in neurodegenerative diseases-What is the evidence

However, after the MT binding capacity is saturated, a large amount of Cd ion is liberated into the cytosol and Cd can directly affect and damage the integrity of plasma membranes and intracellular organelles causing cell death 23,24

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Effect of additional oral semaglutide vs sitagliptin on glycated hemoglobin in adults with type 2 diabetes uncontrolled with metformin alone or with sulfonylurea: the PIONEER 3 randomized clinical trial